What enzyme is most commonly defective in people with phenylketonuria?
-Phenylalanine, which is an amino acid in another amino acid.
What reaction does this enzyme catalyze? What is substrates? and What product is produced?
-The enzyme catalyzes phenylalanine hydroxylase(PAH)
-A block is produced in a biochemical pathway.
-Thyroxine,dopa, and melanin is produced.
Describe the symptoms of phenylketonuria?
-The symptoms for the most severe are infants appear normal until they are a few months, without treatment children develop permanent intellectual disability,seizures,delayed development,behavioral problems,psychiatric problems, musty or mouse-like odors a side effect,children have lighter skin and hair then there parents, and skin disorders such as eczema.
-The symptoms for the less severe have smaller risk of brain damage, babies born to mothers who have it, have ur controlled phenylalanine levels,have a risk of intellectual disability,infants may also have low birth weight and grow more slowly than other children,medical problems,and women with PKU have an increased risk of pregnancy loss.
What causes the symptoms of PKU, the lack of a substance or the buildup of one?
-Enzyme causes it by the build up in the body to high levels.
How common is phenylketonuria? How is it treated?
-Phenylketonuria is a rare inherited condition.
-The treatment is a low protein diet;you can't was alot of meat,cheese,poultry,eggs,and milk.
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